FTO, the gene commonly associated with obesity, may actually contribute to weight gain, a new study has found. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells. Specific abnormalities of cilium molecules, in turn, increase body weight, in some instances, by affecting the function of receptors for leptin, a hormone that suppresses appetite. ...Sunday 25 May 2014
Obesity Gene Linked to Weight Gain
FTO, the gene commonly associated with obesity, may actually contribute to weight gain, a new study has found. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells. Specific abnormalities of cilium molecules, in turn, increase body weight, in some instances, by affecting the function of receptors for leptin, a hormone that suppresses appetite. ...
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