Tuesday, 5 February 2013

Key Moments in Cell Death Captured By Researchers

Dr Czabotar said, "By using the powerful X-ray beams created by the synchrotron, we obtained structures of Bax that were really exciting." "Bax is activated when small protein fragments called BH3-peptides bind to it. We saw that these peptides open up the Bax molecule like a key unlocking a padlock. This unlocked form of Bax can bind to another Bax molecule, which can then form larger Bax complexes that can go on to break up membranes in the cell. "As ...

via Medindia Health News More READ

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