Though a carcinoma "in situ" means a cancer in place, it often does not keep its place. Standing between a cancer cell in situ and the surrounding tissue of fibroblasts and extra-cellular matrix is the basement membrane, a thin sheet of fibers that normally cradles the cells above it. The basement membrane is also the frontline physical barrier that keeps primary tumors from spreading into the matrix below. Perforating the basement membrane is a cancer cell's first move toward ...Sunday 7 December 2014
Scientists Study the Role of Cancer Cells and Some Fibroblasts in the Breakage of Cellular Membrane
Though a carcinoma "in situ" means a cancer in place, it often does not keep its place. Standing between a cancer cell in situ and the surrounding tissue of fibroblasts and extra-cellular matrix is the basement membrane, a thin sheet of fibers that normally cradles the cells above it. The basement membrane is also the frontline physical barrier that keeps primary tumors from spreading into the matrix below. Perforating the basement membrane is a cancer cell's first move toward ...
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