Researchers from the Center for iPS Cell Research and Application (CiRA), Kyoto University have revealed that genetic mutations causing DMD can be corrected using induced pluripotent stem (iPS) cells. The research, published in emStem Cell Reports/em, demonstrates how engineered nucleases, such as TALEN and CRISPR, can be used to edit the genome of iPS cells generated from the skin cells of a DMD patient. The cells were then differentiated into skeletal muscles, in which ...Thursday 27 November 2014
Genetic Mutations Causing Muscular Dystrophy are Corrected Using IPS Cells
Researchers from the Center for iPS Cell Research and Application (CiRA), Kyoto University have revealed that genetic mutations causing DMD can be corrected using induced pluripotent stem (iPS) cells. The research, published in emStem Cell Reports/em, demonstrates how engineered nucleases, such as TALEN and CRISPR, can be used to edit the genome of iPS cells generated from the skin cells of a DMD patient. The cells were then differentiated into skeletal muscles, in which ...
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