Previous research has highlighted that a class of compounds called ADEPs (cyclic acyldepsipeptides) is a promising new weapon in the fight against drug-resistant bacteria. The compounds work by attaching themselves to a cellular enzyme called ClpP, which bacterial cells use to rid themselves of harmful proteins. With an ADEP attached, ClpP can't function properly, and the bacterial cell dies. Now, scientists from Brown University and Massachusetts Institute ...Tuesday, 30 September 2014
New Strategies for Killing TB Bacterium Highlighted in Research
Previous research has highlighted that a class of compounds called ADEPs (cyclic acyldepsipeptides) is a promising new weapon in the fight against drug-resistant bacteria. The compounds work by attaching themselves to a cellular enzyme called ClpP, which bacterial cells use to rid themselves of harmful proteins. With an ADEP attached, ClpP can't function properly, and the bacterial cell dies. Now, scientists from Brown University and Massachusetts Institute ...
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