A form of vitamin A, Retinoic acid, is used to treat and help prevent the recurrence of a variety of cancers, however, some patients do not benefit from the drug. The reason for this resistance was unclear until this week when researchers from Virginia Commonwealth University (VCU) Massey Cancer Center demonstrated that a protein known as AEG-1 blocks the effects of retinoic acid in leukemia and liver cancer. Because AEG-1 is overexpressed in nearly every cancer, these findings ...Friday 15 August 2014
Benefits of Vitamin a Cancer Therapy Blocked by Protein
A form of vitamin A, Retinoic acid, is used to treat and help prevent the recurrence of a variety of cancers, however, some patients do not benefit from the drug. The reason for this resistance was unclear until this week when researchers from Virginia Commonwealth University (VCU) Massey Cancer Center demonstrated that a protein known as AEG-1 blocks the effects of retinoic acid in leukemia and liver cancer. Because AEG-1 is overexpressed in nearly every cancer, these findings ...
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