Research published ahead of print today in the iJournal of Virology/i reveals that a single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice. "Knowing the factors and markers that govern the efficient growth of a virus in one host species, tissue, or cell culture versus another is of fundamental ...Sunday, 3 March 2013
H5N1 Infection of Mammals Enabled by Mutation Altering Stability of Surface Molecule in Acid
Research published ahead of print today in the iJournal of Virology/i reveals that a single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice. "Knowing the factors and markers that govern the efficient growth of a virus in one host species, tissue, or cell culture versus another is of fundamental ...
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