A newborn mammal must survive the sudden loss of food supply from its mother, in the perilous hours immediately after birth. Newborns mount a metabolic response to ward off starvation until feeding occurs, under normal circumstances. This survival response involves a process of controlled breakdown of internal energetic sources known as autophagy. Although autophagy has been well documented, the key mechanistic regulators of autophagy in vivo have remained poorly understood. ...Tuesday, 25 December 2012
In Newborn Mammals Nutrient-sensing Enzymes Key to Starvation Response and Survival
A newborn mammal must survive the sudden loss of food supply from its mother, in the perilous hours immediately after birth. Newborns mount a metabolic response to ward off starvation until feeding occurs, under normal circumstances. This survival response involves a process of controlled breakdown of internal energetic sources known as autophagy. Although autophagy has been well documented, the key mechanistic regulators of autophagy in vivo have remained poorly understood. ...
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