New Views of Enzyme Structures Offer Insights into Metabolism of Lipids Including Cholesterol

With the aid of X-ray crystallography, researchers have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol. The research took place at the University of Michigan. The findings are an important step toward understanding and being able to therapeutically target disorders and drug side effects that cause lipids, including cholesterol, to build up in the body--leading ...

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