Risk of Sudden Cardiac Death Tied to Protein Overproduction

Johns Hopkins scientists report that a genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding DNA, a growing focus of disease research. The discovery, reported in the June 5 issue of emThe American Journal of Human Genetics/em, also adds to scientific understanding of the causes of sudden cardiac death and of possible ways to prevent ...

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