Lung Cancer Patients Who Carry Specific HER2 Mutations may Benefit from Certain Anti-HER2 Treatments

New study suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced non-small cell lung cancer (NSCLC) harboring specific HER2 protein mutations. The retrospective study was conducted in Europe. Although genetic changes cause tumor cells to make too much of the HER2 protein in up to 20% of lung cancers, mutations in the HER2 gene occur in only 1-2% of ...

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