Breast cancer: Scan younger women at risk, charity says

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Knife crime: 1,000 young victims hospitalised last year

The NHS also says there has been a 54% rise in the number of victims aged 10 to 19 over five years. via BBC News - Health Read More Here..

Is young people's mental health getting worse?

Social media and school pressures are often blamed for a rise in young people saying they need help. via BBC News - Health Read More Here..

Calls for change in law on PTSD related deaths

Family and friends of a former soldier who took his own life say more support is needed for those with PTSD. via BBC News - Health Read More Here..

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Tinnitus: What it is like living with the condition

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Tanzania male MPs face circumcision call to stop HIV spread

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'How a smartphone saved my mother's life'

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Venezuela crisis: A health system in a state of collapse

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Mosquitoes given diet drugs 'go off biting'

US scientists say they may have found a way to reduce the appetite of blood-hungry mosquitoes. via BBC News - Health Read More Here..

Vanellope Hope Wilkins: Home for girl born with heart outside body

Vanellope Hope Wilkins has been discharged from hospital after 14 months and three operations. via BBC News - Health Read More Here..

Extreme morning sickness: 'You become a shell of a person'

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Measles cases in Europe tripled last year, WHO says

More than 90% of cases were reported in 10 countries, including France, Italy and Greece. via BBC News - Health Read More Here..

Children and electronic devices - how to keep young people safe

As concerns mount over how screen time and social media affect children, parents are given suggestions. via BBC News - Health Read More Here..

Tinnitus: 'Hearing condition makes me feel trapped'

Music fan Jessica Berg urges young people to wear ear plugs at loud gigs. via BBC News - Health Read More Here..

Assisted dying: 'I wish the law let me have him for longer'

Ann Whaley has travelled to a Swiss clinic with her husband Geoff, who plans to end his life. via BBC News - Health Read More Here..

Measles outbreak declared in Philippines

Health authorities previously warned that more than two million children have not been vaccinated. via BBC News - Health Read More Here..

Yemen conjoined twins: Doctors appeal for help evacuating boys

The newborns need treatment abroad, but commercial planes cannot leave Sanaa because of a blockade. via BBC News - Health Read More Here..

Dementia risk factors not known by half of population

Risk factors for dementia include heavy drinking, smoking, genetics and high blood pressure. via BBC News - Health Read More Here..

More veg, fewer burgers - can a family learn to like the planetary health diet?

One family tell how they adapted to switching their sausages and burgers to tofu and beans. via BBC News - Health Read More Here..

'I won't stop injecting tanning aids despite warnings'

A man who injects an unregulated drug to boost his tan says he will not stop despite health warnings. via BBC News - Health Read More Here..

Can tech help plug the healthcare gap?

Ageing populations around the world are putting pressure on healthcare. Can innovation plug the gap? via BBC News - Health Read More Here..

Chronic conditions: What does ‘healthy’ mean when you have a long-term illness?

For some, this time of year is all about being and keeping ‘healthy’ - but what does ‘healthy’ mean when you have a long-term health condition? via BBC News - Health Read More Here..

Nurse denies raping incapacitated patient

Nathan Sutherland appeared in court to deny charges that he sexually assaulted the disabled patient. via BBC News - Health Read More Here..

Air pollution: 'Our children are suffocating'

The UN agency Unicef says around 1 in 3 British children live in areas with unsafe levels of pollution via BBC News - Health Read More Here..

Exploding e-cigarette kills 24-year-old Texas man

The pen exploded when the man tried to use it, causing what is at least the second such death in the US. via BBC News - Health Read More Here..

Hawaii may increase legal smoking age to 100

If the law passes, people in Hawaii won't be able to buy cigarettes until they are a century old. via BBC News - Health Read More Here..

Acid attacks: Cambodia victims 'denied government aid'

Human Rights Watch interviewed 17 victims who were reportedly not given free treatment. via BBC News - Health Read More Here..

Zimbabwe pastor Walter Magaya convicted over 'HIV cure'

Walter Magaya falsely claimed that a herb-based drug had the magical power to cure HIV and Aids. via BBC News - Health Read More Here..

Instagram's most-liked egg is actually a mental health advert

The image of an egg, which is Instagram's most liked photo ever, is part of a mental health campaign. via BBC News - Health Read More Here..

'X-factor' golf swing linked to back pain

Going for a supercharged swing could play havoc with your back, according to spine surgeons. via BBC News - Health Read More Here..

Carers quitting jobs from pressure

More than 600 people a day leave their jobs because of the demands of being a carer for a relative. via BBC News - Health Read More Here..

Fake Xanax: Anxiety drug deaths an 'escalating crisis'

Northern Ireland's chief coroner speaks out over the rising number of deaths linked to the anti-anxiety drug. via BBC News - Health Read More Here..

FGM: 'The cruellest thing'

A victim of Female Genital Mutilation speaks out about her experience after the UK’s first successful conviction. via BBC News - Health Read More Here..

'I wish I could just have a normal life'

"Life-extending" drugs for those with cystic fibrosis are unavailable due to a dispute over cost. via BBC News - Health Read More Here..

Obesity-related cancers rise for younger US generations, study says

The problem could become worse as young people age, the American Cancer Society's study says. via BBC News - Health Read More Here..

FGM 'increasingly performed on UK babies'

One expert says it is "almost impossible" for authorities to detect it when done at such a young age. via BBC News - Health Read More Here..

Deadlock must end over cystic fibrosis drug Orkambi

Vertex, which makes Orkambi, has refused a £500m offer for the drug over five years via BBC News - Health Read More Here..

Parents of deaf children face funding 'postcode lottery'

A "postcode lottery" means parents of four-month-old Lola have to pay for sign language classes. via BBC News - Health Read More Here..

Which countries eat the most meat?

Many in the West say they are trying to cut down on meat, but the reality is a different story. via BBC News - Health Read More Here..

Giving a voice to my friend’s songs

When Bernie was struck by motor neurone disease, a friend helped grant his lifelong wish. via BBC News - Health Read More Here..

Fighting 'all you can eat' waste

The UN wants to halve the amount of food we waste. Here's how one hotel in Norway is helping out. via BBC News - Health Read More Here..

French rugby players' deaths raise concern over safety

French rugby is currently under a shadow cast by the deaths of four players in the past eight months via BBC News - Health Read More Here..

New Treatment for Acquired Thrombotic Thrombocytopenic Purpura: Caplacizumab

Immune-mediated deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained adhesion of von Willebrand factor multimers to platelets and microthrombosis. This results in thrombocytopenia, hemolytic anemia, and tissue ischemia. These are the hallmarks of  acquired thrombotic thrombocytopenic purpura (TTP).

Caplacizumab is an anti–von Willebrand factor humanized. Caplacizumab is not a full antibody, but just a fragment if it, as you can see in the video below. It inhibits interaction between von Willebrand factor multimers and platelets.

In this double-blind, controlled trial, 145 patients with TTP received caplacizumab (10-mg intravenous loading bolus, followed by 10 mg daily subcutaneously) or placebo during plasma exchange and for 30 days thereafter.

The median time to normalization of the platelet count was shorter with caplacizumab than with placebo (2.69 days vs. 2.88 days). Patients who received caplacizumab were 1.55 times as likely to have a normalization of the platelet count as those who received placebo.

Treatment with caplacizumab in TTP was associated with:

- faster normalization of the platelet count
- lower incidence of a composite of TTP-related death, recurrence of TTP, or a thromboembolic event
- lower rate of recurrence of TTP



References:

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura | NEJM https://buff.ly/2MMYBLr</0>

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