Bottom Line: Cerebral spinal fluid (CSF) levels of (and) #946;-amyloid 42(A (and) #946;42) are linked with the diagnosis of Alzheimer disease (AD) and (A (and) #946;) accumulation in the brain independent of apolipoprotein E (APOE) gene makeup. Authors: Ronald Lautner, M.D., of Sahlgrenska University Hospital, Sweden, and colleagues. Background: With the emergence of biomarker dementia diagnostics, interest in CSF biomarkers associated with AD, including A (and) #946;42 and ...The Great Place for all lake forest health and fitness | island health and fitness | health and fitness blogs Health and Fitness Blog Information and News.
Monday, 1 September 2014
Diagnostic Accuracy of Cerebral Spinal Fluid Biomarkers for Alzheimer Disease
Bottom Line: Cerebral spinal fluid (CSF) levels of (and) #946;-amyloid 42(A (and) #946;42) are linked with the diagnosis of Alzheimer disease (AD) and (A (and) #946;) accumulation in the brain independent of apolipoprotein E (APOE) gene makeup. Authors: Ronald Lautner, M.D., of Sahlgrenska University Hospital, Sweden, and colleagues. Background: With the emergence of biomarker dementia diagnostics, interest in CSF biomarkers associated with AD, including A (and) #946;42 and ...30 Delicious Things To Cook In September
I look forward to sweater season every year because it means I can eat more.
WHAT'S IN SEASON:
(This will vary depending on time of the month and where you live)
Apples
Arugula
Beans
Beets
Corn
Cucumbers
Eggplant
Fennel
Figs
Grapes
Mangoes
Melons
Okra
Pears
Peppers
Plums
Pumpkins
Raspberries
Shallots
Sorrel
Summer squash
Tomatoes
Watercress
Watermelon
Winter squash
Upside-Down Plum Cake
This seriously beautiful dessert is also super easy to make. Recipe here.
redstartolonestar.blogspot.com
Garlic Butter Salmon with Caramelized Shallot Relish
Recipe here.
23 Easy And Delicious Things You Can Do With Pita Bread
Keep these in your back pocket . (Get it?)
Breakfast Pita Pizza
Breakfast pizza rules, but who has time to mess with dough before noon? This is the solution. Get the recipe.
Lisa Lavery / chow.com
Whole Wheat Pita Pockets with Romaine, Roasted Beets, Chicken & Manchego Cheese
Bring this to work on Monday and you'll feel like a baller all week. Get the recipe.
Emma Christensen / thekitchn.com
JalapeƱo Popper Pita Pizza
A super-swanky ranch and cream cheese sauce topped with chicken, jalapeƱos, cheddar, and crispy panko breadcrumbs. Get the recipe.
Shawn Syphus / iwashyoudry.com
India's Cipla launches copy of GSK's top asthma drug in Germany, Sweden
Oxidized Lipids may be a Key to Treating Pulmonary Hypertension
Oxidized lipids are known to play a key role in hardening arteries and inflaming blood vessels, which causes diseases like atherosclerosis. A new study at UCLA demonstrates that they may also contribute to pulmonary hypertension, a serious lung disease that narrows the small blood vessels in the lungs. Using a rodent model, the researchers showed that a peptide mimicking part of the main protein in high-density lipoprotein (HDL), the so-called "good" cholesterol, ...The High Cost of Hot Flashes
The steep decline in the use of hormone therapy has spawned a prevalent but preventable side effect: thousands of women suffering in silence with hot flashes. This is according to a study by a Yale School of Medicine researcher and colleagues. In the study published in the Aug. 27 online issue of the journal iMenopause/i, the team found that moderate to severe hot flashes - also called vasomotor symptoms (VMS) - are not treated in most women. Women with VMS ...Facing the Future
Nine years have passed since the first partial face transplant was performed in France but the questions regarding both the physical and psychological ramifications for patients remain.
One of my first contributions to Brain Blogger examined the debate surrounding face transplantation, written in 2008 after the completion of the first partial procedure in the United States. A few days ago, GQ Magazine announced that Richard Norris, the recipient of the first successful complete face transplant, had been photographed and interviewed for the latest edition of the monthly publication. His surgery was performed in 2012 by Dr. Eduardo Rodriguez, a Baltimore plastic surgeon, in a 35 hour procedure.
Unlike a presentation in a medical journal which would focus more on clinical outcomes, the GQ feature is a short narrative of a day in Norris’ life spent with journalist Jeanne Marie Laskas. It addresses some of the questions raised in the beginning when this procedure was proposed.
From Laskas’ account, Norris and his family are proud of the role that he has played in the advancement of medicine despite the many restrictions imposed on him. Like any other transplant, there is a risk of rejection and he will require a strict lifelong regimen of medications that leave him at risk of disease due to being immunocompromised. However Norris enjoys being able to walk through life without a mask over his face as he did in the past. While article reports his difficulties as a patient, he also attends medical meetings as an example of how positive this surgery can be for patients and as a role model for further developments.
Earlier this year in April, Dr. Rodriguez and his colleagues were published in scientific journal The Lancet reviewing the 28 face transplantation cases that have been performed around the world. The study shows that none of the patients have reported any psychiatric difficulties, have accepted their new physical appearance and that some have returned to work. Functional and neurological results have also been favorable.
However, some data are limited as there is not currently a standardized reporting method for outcomes to be measured and follow-up to date remains short-term. As the medical teams involved perform more of these surgeries and the number of patients increase, we will begin to have a clearer picture of the effects on all aspects of their lives.
The benefits of facial transplantation lie beyond the aesthetic for patients who have sustained severe trauma. The ability to see, begin the process of food digestion, and speech can all be affected by injury or disease. The ability to restore all of these functions and others requires transplantation of soft tissue, bone, nerves and blood vessels from the recipient to the donor in a technically complex surgery. The key to successful long-term outcome lies not only with the operation itself but also in establishing a multidisciplinary team to monitor patients mental and physical well-being following recovery.
The debate is certainly not over regarding the long-term implications of this surgery, but for patients like Richard Norris the risk appears to be worth it.
References
Khalifian S, Brazio PS, Mohan R, Shaffer C, Brandacher G, Barth RN, & Rodriguez ED (2014). Facial transplantation: the first 9 years. Lancet PMID: 24783986
Laskas, Jeanne Marie. July 2014. The New Face of Richard Norris. GQ Magazine
Image via ChaNaWiT / Shutterstock.
via Brain Blogger Read More Here..
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Better Health Care Important to Control Risk Factors for Heart Health
Keeping a healthy heart may have as much to do with the quality of health care you have and avoiding risk factors such as smoking, bad diet and little exercise. A large international study led by researchers at the Population Health Research Institute at McMaster University and Hamilton Health Sciences has found a that low-income countries which have people with the lowest risk factors for cardiovascular problems have the highest rates of cardiovascular events ...Wolves may be Susceptible to Yawn Contagion: Study
A study published August 27, 2014 in the open-access journal iPLOS ONE/i by Teresa Romero and colleagues from The University of Tokyo, Japan, suggest that wolves may be susceptible to yawn contagion. Researchers suggest that contagious yawning may be linked to human capacity for empathy, but little evidence apart from studies on primates, exists that links contagious yawning to empathy in other animals. Recently, researchers have documented domestic dogs demonstrating ...