Study helps explain chronic inflammation in autoimmunity and cancer

Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in the journal Science Translational Medicine.An increase in beta-catenin in certain types of T cells - a class of white blood cells - causes chronic inflammation in the intestine and colon, eventually leading to cancer. The same mechanism is used by colon cancer to propagate itself. via Health News from Medical News Today Read More Here..