Enhanced Anti-HIV Activity Discovered In Potential Drug Molecule

Researchers from Munich and Naples have shown that minimal modification of a synthetic peptide with anti-HIV activity results in a new compound with more than two orders of magnitude higher binding affinity to the chemokine receptor CXCR4 and greatly improved anti-HIV activity. This could be a step toward the design of new, more effective drugs against AIDS, inflammatory diseases, and some forms of cancer. Different strains of HIV-1 use either the chemokine receptor CCR5 or CXCR4 for entry into immune cells... via Health News from Medical News Today Read More Here..