Monday, 27 June 2016

Euro 2016: Football alcohol adverts seen 'once a minute'

People who watched Wales' Euro 2016 game against England on television saw alcohol marketing almost once every minute during play, a study finds. via BBC News - Health Read More Here..

High sport drink use among young teens 'risk to health'

High numbers of younger teenagers are risking tooth decay and obesity by regularly having high-sugar sport drinks, dental experts say. via BBC News - Health Read More Here..

Office cake culture is 'danger to health'

Having cake at work to celebrate colleagues' birthdays, engagements or just surviving the week is a danger to health, warns a senior dentist. via BBC News - Health Read More Here..

GPs to receive help to improve patients’ physical activity

RCGP announces physical activity and lifestyle as new clinical priorities

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Experts call for more realistic physical activity targets
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via OnMedica News Read More Here..

50% drop in rate of hospital acquired foot ulcers, audit shows

Little improvement on other patient harms and lack of specialist staff

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Annual diabetes checks still being missed
Diabetics suffer 200,000 complications per year
Poor diabetes education leading to health complications
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NHS must hold CCGs accountable for poor diabetes care
via OnMedica News Read More Here..

Hundreds of genes seen sparking to life two days after death

The discovery that many genes are still working up to 48 hours after death has implications for organ transplants, forensics and our very definition of death via New Scientist - Health Read More Here..

Alcohol adverts shown every 72 seconds during Euro 2016

Campaigners warn about ‘enormous’ levels of alcohol promotion

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Alcohol-related deaths rise 5% in a year
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Experts reject BMA stance on vaping

BMA policy may undermine stop smoking efforts

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E-cigarettes 95% less harmful than tobacco
Teenagers who vape more likely to progress to smoking, study shows
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Extra money for NHS from Brexit in doubt

Campaigners deny full promise of NHS cash boost from leaving EU

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Sunday, 26 June 2016

Unpaid carers support group launched

A support group for unpaid carers is set up so people can finally know their rights. via BBC News - Health Read More Here..

Can We Predict Which People Will Be Better At Learning Foreign Languages?

One common gripe we probably have when we observe that friend who can speak effortlessly in a dozen different tongues may be something along the lines of: “Why is he or she so good at learning languages – it’s not fair!” Well, now it appears that perhaps there is indeed some hidden advantage this friend has over ourselves: How our brain is “wired” affects how we pick up a new language.

A recent study has shown for the first time that people who have difficulty in learning a new language could have brains that are wired in a way that reduces their ability to acquire the necessary linguistic skills. In particular, this means that the intrinsic differences in how different brain regions communicate with each other makes it significantly easier for some adults to learn a second language as compared to others.

Scientists now are able to use brain scans to effectively determine how good a person’s language acquisition abilities are. It turns out that this is directly linked to the ability of the communication of the brain’s language centres when we are in a state of rest. The reason for this is that a large part of our learning processes actually occurs when we are resting – indeed, it is not surprising that sleep is of critical importance to both our learning and health.

Now, scientists have discovered that the learning of language is considerably easier if there is a higher degree of communication between two regions of the brain, more specifically when the left anterior operculum interacts more with the left superior temporal gyrus (an integral part of the language network in our brains). This has strong implications for predicting the ease (or lack thereof) at which one can learn a new language.

The study described herein involved a total of 15 English-speaking adults who were about to enlist in a course to learn French that spanned 12 weeks of intensive training. Prior to and after the course, the brains of these participants were scanned and their language abilities were tested. It was shown that those who had improved connections between the aforementioned brain regions demonstrated a much bigger degree of improvement in the administered speaking test, highlighting the important role brain wiring plays in language acquisition.

Brain rhythm patterns and the ability to learn a foreign language

In addition to the inherent “wiring” of the brain, it has also been shown recently in a separate study that the brain rhythm patterns of an adult can be another good predictor of how well he or she can learn a new language – and this measurement of brain activity during a resting state only takes a mere five minutes. In this study, scientists show that the brain’s resting state rhythms could be analyzed for characteristics that account for 60% of the variability influencing an adult’s ability to acquire a second language. The participants in this study were 19 adult volunteers with ages ranging from 18 to 31 years without any prior experience with learning French. With their eyes closed, the volunteers sat for five minutes. During this time period, they were equipped with an EEG (electroencephalogram) headset, which served to provide measurements of brain activity patterns.

For the length of the study, which took place over a total of eight weeks, the volunteers went to the lab two times a week to take part in French lessons with each lasting 30 minutes. These language-training lessons were administered via a computer utilizing an immersive virtual reality program funded by the United States Office of Naval Research. The program is termed the Operational Language and Cultural Training System (OLCTS), and seeks to enable members of the military to gain rudimentary proficiency in a new language with only 20 training hours. Notably, the program is self-paced and provides a sequence of stories and scenes to facilitate learning. A component to recognize voices is also incorporated to allow for easy verification of pronunciation.

Additionally, the scientists included quizzes at various points in the course that required a minimum score before allowing participants to move on to the subsequent lesson. This ensured that the users were attentive when going through the lessons and also doubled as an indicator of the speed at which each user went through the designated syllabus.

After the conclusion of this training regimen, the volunteers took a test that assessed their proficiency in the new language (the coverage of the test was based on the number of lessons completed). Even though the fastest participant learned twice as quickly as the slower ones, the latter learned just as well in terms of their language proficiency. From the EEG headsets, the recordings showed that specific brain activity patterns that were linked to language-related processes had the highest correlation to the volunteers’ ability to pick up a new language, indicating that these patterns could plausibly confer some inherent benefits for people looking to learn a second language.

Are “brain advantages” the only determinants of language learning?

In the light of the findings described in this article, it is pertinent to note that the brain’s wiring does not unequivocally predetermine a person’s ability to learn a new language, given that there are many other innate as well as environmental factors involved, such as the motivation of the individual. In a similar train of thought, this does not mean that people without the “advantageous” brain pattern should not try learning a second language as such a pattern only accounts for 60% of the variability in language acquisition. This means that other factors play important roles in the learning process and should be taken into account as well.

The brain’s plasticity means that different learning stimuli and experiences can shape how it develops. To this end, these studies provide key insights into how the learning of a new language can be influenced in individual-specific differences. In this regard, it would logically follow that the long-term goal would be to eventually develop more targeted approaches for individuals to facilitate their language acquisition.

Moreover, brain activity in the resting state can be modified using a type of training dubbed neurofeedback training, for which work is ongoing currently. This program regimen allows users to strengthen brain patterns related to enhanced cognition in order to improve their performance in language learning. Hopefully, this can subsequently be extended to improving learning abilities in general in the future – an exciting concept with boundless applications.

References

Berken, J., Gracco, V., Chen, J., Watkins, K., Baum, S., Callahan, M., & Klein, D. (2015). Neural activation in speech production and reading aloud in native and non-native languages NeuroImage, 112, 208-217 DOI: 10.1016/j.neuroimage.2015.03.016

Chai, X., Berken, J., Barbeau, E., Soles, J., Callahan, M., Chen, J., & Klein, D. (2016). Intrinsic Functional Connectivity in the Adult Brain and Success in Second-Language Learning Journal of Neuroscience, 36 (3), 755-761 DOI: 10.1523/JNEUROSCI.2234-15.2016

Gruzelier, J. (2014). EEG-neurofeedback for optimising performance. I: A review of cognitive and affective outcome in healthy participants Neuroscience & Biobehavioral Reviews, 44, 124-141 DOI: 10.1016/j.neubiorev.2013.09.015

Prat, C., Yamasaki, B., Kluender, R., & Stocco, A. (2016). Resting-state qEEG predicts rate of second language learning in adults Brain and Language, 157-158, 44-50 DOI: 10.1016/j.bandl.2016.04.007

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Friday, 24 June 2016

Making Decisions on a “Hangry” Impulse

“Hangry” is slang for that feeling of anger you may get when you’re hungry. It’s very common, in my experience… My friendly advice: don’t make any important decisions when you’re hungry. Why? Because you’re more likely to act on an impulse. And this is not just a personal conclusion: this was actually the main finding of a study carried out at The Sahlgrenska Academy of the University of Gothenburg in Sweden, and recently published at Neuropsychopharmacology.

Impulsivity is a form of impaired decision-making wherein decisions are made with a lack of ability to plan for the future. Broadly speaking, impulsivity includes two components: impulsive actions and impulsive choices. These impulsive behaviors are characteristic of many psychiatric and behavioral disorders, such as gambling, substance abuse, eating disorders, for example. Research on the neurobiological mechanisms of impulsivity has established a role for some major neurotransmitters, including dopamine and serotonin.

But where does hunger fit into this? Apparently, the gut has a word to say when it comes to impulsivity. Both dopamine and serotonin are known to be modulated by a hormone that is produced by the stomach – ghrelin. Ghrelin is an appetite stimulant, which means that its levels increase during the initial period of food restriction, and this increase acts as a trigger for hunger, thereby leading to food intake. Ghrelin also increases the rewarding feeling of food through the action of dopamine and opioids. Food reward is in turn known to be positively correlated with impulsivity. And ghrelin seems to influence dopamine release in areas of the brain associated with increased impulsivity in humans. Ghrelin can also increase the levels of dopamine and the activity of dopaminergic neurons in areas of the brain associated with motor control and is thereby potentially associated with motor impulsivity.

Take together, this suggests that ghrelin may theoretically act as a neurobiological regulator of impulsivity. And that was precisely what the study mentioned above aimed to determine. The authors assessed the role of ghrelin on impulsive behavior, namely on the ability to inhibit or restrain a behavioral response and to delay gratification.

Their work showed that ghrelin increases impulsivity in rats that had to perform different tasks of impulsive responding, being able to affect both impulsive actions and impulsive choices. When a large food reward could be obtained without delay, ghrelin administration predisposed the animals to selecting that larger food reward; nothing surprising here – more food sounds like an obvious choice. But when obtaining a larger reward required waiting, a smaller but immediate reward became preferred. This revealed that ghrelin administration led to an inability to delay gratification, which is a manifestation of impulsive behavior.

Ghrelin’s association with dopamine release was also studied and it was shown that ghrelin administration led to an increase in the levels of dopamine in areas of the brain associated with impulsive behavior. Ghrelin treatment caused a reduction in the expression of an enzyme responsible for dopamine degradation, consequently leading to an accumulation of the neurotransmitter in that area. Reduced activity of that enzyme (Catecol O-Metiltransferase – COMT) is actually associated with attention-deficit/hyperactivity disorder and obsessive-compulsive disorder in humans, two conditions in which impulsive behaviors are paramount. This sustained the hypothesis that ghrelin’s effect on impulsivity occurs, at least partially, through the action of dopamine.

Besides explaining why we become so impulsive when we need food, this study also establishes another link between the gut and the brain: it shows how a gut-produced hormone regulates neurobiological mechanisms of impulsive behavior.

So, remember: whenever you get “hangry”, you can blame it on ghrelin. I sure will!

References

Abizaid, A. (2009). Ghrelin and Dopamine: New Insights on the Peripheral Regulation of Appetite Journal of Neuroendocrinology, 21 (9), 787-793 DOI: 10.1111/j.1365-2826.2009.01896.x

Anderberg, R., Hansson, C., Fenander, M., Richard, J., Dickson, S., Nissbrandt, H., Bergquist, F., & Skibicka, K. (2015). The Stomach-Derived Hormone Ghrelin Increases Impulsive Behavior Neuropsychopharmacology, 41 (5), 1199-1209 DOI: 10.1038/npp.2015.297

Bizot, J., Le Bihan, C., Puech, A., Hamon, M., & Thiébot, M. (1999). Serotonin and tolerance to delay of reward in rats Psychopharmacology, 146 (4), 400-412 DOI: 10.1007/PL00005485

Cheuk, D., & Wong, V. (2006). Meta-analysis of Association Between a Catechol-O-Methyltransferase Gene Polymorphism and Attention Deficit Hyperactivity Disorder Behavior Genetics, 36 (5), 651-659 DOI: 10.1007/s10519-006-9076-5

Menzies JR, Skibicka KP, Leng G, & Dickson SL (2013). Ghrelin, reward and motivation. Endocrine development, 25, 101-11 PMID: 23652396

Image via Olichel / Pixabay.

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Diabetes Plus Kidney Problems May Raise Heart Risks

Odds of death due to heart disease 15 percent higher in black Americans with both conditions, study finds

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Drug Monitoring Programs Do Curb Overdose Deaths: Study

Opioid epidemic demands such measures, researcher says
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Keep Safe When Temperatures Soar

Everyone's at risk of heat-related illness, but elderly are most vulnerable, ER specialist says

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Fiber: The Rx for Disease-Free Aging

Lots of this dietary nutrient can keep you healthy, functioning, study suggests

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Healthy Living Slashes Cancer Risk

The 'good' life cuts tumor odds up to 45 percent and risk of cancer death up to 61 percent, study finds

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Southern States Lagging in Tough Smoking Bans, CDC Says

Only 6 in 10 Americans covered by state or local laws banning smoking in public places

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Dengue Virus May Bolster Zika's Attack

Prior exposure to this other mosquito-borne virus might worsen infection, study says

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Guidelines Stop Heat Stroke Deaths in High School Athletes

Protocols help get students used to the heat during preseason practice

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Sprained Ankle Could Pose Longer-Term Harms to Health

Study finds link between adult injury, more heart and lung problems later

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CDC Panel Says FluMist Nasal Flu Vaccine Ineffective

Agency advisors say the product has lost potency in kids and shouldn't be used in upcoming season

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Scans May Spare Some Hodgkin Lymphoma Patients from Chemo

Test finds those who might respond well, may spare others treatment side effects

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U.K. Case of Throat Gonorrhea Resists Antibiotics

U.S. officials concerned about potential danger of untreatable STD
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Tourists pick up antibiotic-resistance genes in just two days

When you travel to countries such as South Korea, India and China, it takes just days for your gut flora to acquire genes that make bacteria resistant to antibiotics via New Scientist - Health Read More Here..

New life form discovered in saliva is linked to human disease

Bacteria that parasitise other bacteria have been found for the first time, and are linked to gum disease, cystic fibrosis and antimicrobial resistance via New Scientist - Health Read More Here..

Hundreds of genes seen sparking to life two days after death

The discovery that many genes are still working up to 48 hours after death has implications for organ transplants, forensics and our very definition of death via New Scientist - Health Read More Here..

Nasal spray flu vaccine for children proving effective

Vaccine thought to be 57.6% effective in preventing child flu

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UK’s vote to leave EU will impact on NHS

David Cameron to step down as Prime Minister

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Dual treatment possible for diabetes and Alzheimer’s disease

Study finds new link between diabetes and Alzheimer’s

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Genetically caused low birthweight linked to diabetes risk

Each genetic risk score point increases diabetes risk by 6%

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Leader thanks GPs for their support during strike action

BMA says profession is united following strike action

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On The Pulse - June 2016

Stem-cell transplantation for multiple sclerosis
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Whole Genome Sequencing: Cracking the Genetic Code for Foodborne Illness

Source: Food and Drug Administration
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Thursday, 23 June 2016

Male infertility cure will be gateway to editing our kids’ genes

The first use of germline genetic engineering could be to treat infertility in men, paving the way for its wider use, says Michael Le Page via New Scientist - Health Read More Here..

Abortion Rates Rising in Zika-Affected Countries, Study Shows

Brazil, Ecuador have seen requests to a women's helpline double in 2016 over prior rates

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Doing This At Bedtime Could Temporarily Rob Your Sight

It's a common activity in today's digital world, leading some to fear blindness, researchers say

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Tighter Opioid Laws in U.S. Haven't Eased Misuse

Study of disabled workers finds no change in painkiller use, overdoses

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Zika Can Also Strike Eyes of Adults: Report

Case of man with potentially severe condition suggests virus can damage vision in more than babies

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Hair Removal for A Beach-Ready Body? Do It Safely

Dermatologist explains healthiest way to remove excess hair with at-home waxing
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Heart Attack Help? There's an App for That

Emergency medicine specialist says technology's potential in health care remains largely untapped

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Women Get Worse Cardiac Arrest Care Than Men

They need to be treated as aggressively as men when their hearts stop, experts say

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A Little Guidance Is Key to Getting That Cancer Screen

Study shows how one hospital's 'patient navigators' boosted testing rates

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Irregular Heartbeat More Deadly in Blacks

They were twice as likely to suffer stroke, heart failure and death than whites with atrial fibrillation
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Alternative Medicine Taking Hold Among Americans: Report

More than $30 billion paid out-of-pocket for acupuncture, yoga, chiropractic care, supplements
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Behavior Woes Hamper Boys More Than Girls in School

They were more likely to be held back, punished, although they also were more likely to have issues

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Many Male Docs May Overlook Female Heart Risks

French team say search of health records finds gender gap

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New life form discovered in saliva is linked to human disease

Bacteria that parasitise other bacteria have been found for the first time, and are linked to gum disease, cystic fibrosis and antimicrobial resistance via New Scientist - Health Read More Here..

Fixed by light: Flick a switch to banish pain and blindness

Parkinson's, blindness, chronic pain and more could all be cured using optogenetics – a revolutionary therapy that has just begun its first trial in humans via New Scientist - Health Read More Here..

Hundreds of genes seen sparking to life two days after death

The discovery that many genes are still working up to 48 hours after death has implications for organ transplants, forensics and our very definition of death via New Scientist - Health Read More Here..