Mice studies have revealed that loss of one of sirtuin (SIRT1) enzyme drives the formation of early prostate cancer (prostatic intraepithelial neoplasia, PIN). SIRT1 can defend the cell against damage from free radicals. Researchers created a mouse model that lacked SIRT1. Normally SIRT1 proteins help activate a mitochondrial protein called SOD2, in turn activating those proteins to keep free-radical levels in check. When SIRT1 levels diminish, SOD2 is no longer effective ...
via Medindia Health News More READ
via Medindia Health News More READ
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