A cell receptor widely involved in intracellular calcium signaling - the IP3R receptor - can be locked into a closed state by enzyme action. This was discovered by researchers from the RIKEN Brain Science Institute in Japan, in collaboration with Juntendo University and the Japan Science and Technology Agency. The locking may potentially play a role in the reduction of neuron signaling seen in neurodegenerative diseases such as Huntington's and Alzheimer's disease. In ...Tuesday 9 September 2014
Neurodegeneration Results from Broken Signals
A cell receptor widely involved in intracellular calcium signaling - the IP3R receptor - can be locked into a closed state by enzyme action. This was discovered by researchers from the RIKEN Brain Science Institute in Japan, in collaboration with Juntendo University and the Japan Science and Technology Agency. The locking may potentially play a role in the reduction of neuron signaling seen in neurodegenerative diseases such as Huntington's and Alzheimer's disease. In ...
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