Medical sciences widely use mouse models of human diseases as essential research tools to increase our understanding in the pathogenesis and pathophysiology of various diseases, and to search for cures. Despite the widespread use of mice as animal models of disease, in 2013, Seok et al. reported that mouse models poorly mimic human inflammatory diseases, such as severe burn injury, sepsis, and acute infection, in terms of gene expression (PNAS 2013, 110(9), 3507-3523), which ...Tuesday 5 August 2014
Mouse Models Not Suitable for Studying Human Disorders
Medical sciences widely use mouse models of human diseases as essential research tools to increase our understanding in the pathogenesis and pathophysiology of various diseases, and to search for cures. Despite the widespread use of mice as animal models of disease, in 2013, Seok et al. reported that mouse models poorly mimic human inflammatory diseases, such as severe burn injury, sepsis, and acute infection, in terms of gene expression (PNAS 2013, 110(9), 3507-3523), which ...
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment