An experimental cocktail of three drugs can dramatically shorten the time it takes to treat patients infected with TB strains that are hard to cure with conventional antibiotics, according to research presented Monday at the world AIDS forum. Dubbed the PaMZ regimen, the drugs killed more TB bacteria than standard therapy and at a faster rate in a so-called Phase IIb trial, usually the penultimate step in vetting new treatments for safety and effectiveness, investigators said. If funding is found, PaMZ will move to Phase III tests by the end of the year, their backers, TB Alliance, said. These resistant strains are especially dangerous for people co-infected with the human immunodeficiency virus (HIV), which causes AIDS.
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