A gene called Lin28 is found to be linked to nearly one-third of cases of Wilms tumor, a pediatric cancer according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms. Studies in the mouse model further suggest that controlled expression of Lin28 can ...Monday 14 April 2014
New Strategy for Kidney Regeneration Suggested by Gene Linked to Pediatric Kidney Cancer
A gene called Lin28 is found to be linked to nearly one-third of cases of Wilms tumor, a pediatric cancer according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms. Studies in the mouse model further suggest that controlled expression of Lin28 can ...
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